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產品名稱:anti-mouse CD154 Biotin MR1 50 ug
產品貨號:eBioscience 13-1541-81
產品規格:50 ug
Anti-Mouse CD154 (CD40 Ligand) Biotin
Also known as: CD40L, Ly-62, Tnfsf5, TRAP
Clone: MR1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-1541
Cat. No. Size
13-1541-81 50 ug
13-1541-82 100 ug
13-1541-85 500 ug
Description: The MR1 monoclonal antibody reacts with mouse CD154, a 39 kDa transmembrane glycoprotein also known as gp39 and CD40 ligand (CD40L). gp39 is expressed transiently by activated T cells and through its binding to CD40 on antigen presenting cells including B cells, monocytes/macrophages and dendritic cells, serves a crucial function in T-APC cognate interaction. gp39 interaction with CD40 transduces signals for T-dependent B cell activation and induces B cell cycle entry.
For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.