產(chǎn)品名稱：anti-mouse IL-21 Receptor Biotin eBio4A9 50 ug 產(chǎn)品貨號(hào)：eBioscience 13-1219-81 產(chǎn)品規(guī)格：50 ug Anti-Mouse IL-21 Receptor Biotin Also known as: Interleukin-21 Receptor, IL-21R Clone: eBio4A9 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 13-1219 Cat. No. Size 13-1219-81 50 ug 13-1219-82 100 ug 13-1219-85 500 ug Description: The IL-21 receptor (IL-21R) combines with the common γ-chain to form a functional receptor for IL-21. IL-21R is expressed on several lineages including both resting and activated B, T, natural killer and dendritic cells. Binding of its ligand, IL-21, in these cells results in the activation of the Jak/Stat signal transduction pathway. The biological effects of ligand binding are diverse and depend on the cellular context and differentiation state of the cell. In the mouse, IL-21 binding to IL-21R induces the apoptosis of resting and activated B cells, enhances anti-CD3-mediated proliferation of T cells, and inhibits the maturation of dendritic cells and the IL-15-mediated expansion of NK cells.
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