eBioscience 13-0411-81 anti-mouse CD41 (MWReg30) Biotin eBioMWReg30 (MWReg30) 5

產品名稱：anti-mouse CD41 (MWReg30) Biotin eBioMWReg30 (MWReg30) 50 ug
產品貨號：eBioscience 13-0411-81
產品規格：50 ug
Anti-Mouse CD41 Biotin
Also known as: fibrinogen receptor, gpIIb/IIIa, integrin alpha Iib
Clone: eBioMWReg30 (MWReg30)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-0411
Cat. No. Size
13-0411-81  50 ug 
13-0411-82  100 ug 
13-0411-85  500 ug 
Description: The eBioMWReg30 monoclonal antibody reacts with mouse CD41 (fibrinogen receptor, gpIIb, integrin alpha IIb). While initially thought to be expressed exclusively on the surface of platelets and megakaryocytes, it has been demonstrated that CD41 is also expressed on hematopoietic progenitors in the embryo, fetus and *****. CD41 associates with CD61 (gpIIIa, integrin beta III) to form a receptor which plays a major role in platelet function, including binding of several adhesion molecules such as fibrinogen, fibronectin and vitronectin.
Recently, the SLAM-family markers, CD48 and CD150 have been used to reliably identify hematopoietic stem cells (HSC). Specifically, it was found that CD150+CD48- bone marrow cells were highly efficient in their ability to confer long-term multi-lineage reconstitution in irradiated mice. Furthermore, the efficiency of reconstitution was enhanced when HSCs were further enriched through the exclusion of CD41+ cells. Thus, the use of CD150+CD48-CD41- as an expression profile efficiently identifies hematopoietic stem cells.
 

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!