eBioscience 12-9955-41 anti-human alpha beta TCR PE (clone: WT31) 25 tests

產品名稱：anti-human alpha beta TCR PE (clone: WT31) 25 tests
產品貨號：eBioscience 12-9955-41
產品規格：25 tests
Anti-Human alpha beta TCR PE
Also known as: abTCR, TCRab
Clone: WT31
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-9955
Cat. No. Size
12-9955-41  25 tests 
12-9955-42  100 tests 
Description: This WT31 monoclonal antibody recognizes the human αβ T cell receptor (TCR) complexed with the CD3ε chain. Composed of a 44-kDa α and a 37-kDa β chain, TCR specificity is typically determined by Vα, Jα, Vβ, Dβ, and Jβ gene rearrangement. The TCR is often associated with the CD3 complex, which is composed of at least five polypeptides. The TCR/CD3 complex recognizes and binds to major histocompatibility complex-bound antigen presented by antigen presenting cells such as B cells, dendritic cells, and macrophages. These events lead to T cell activation, resulting in cellular signaling and cytokine production.
The WT31 monoclonal antibody has been reported to induce proliferation of resting T cells, as well as inhibit cytotoxic T cell activity. In addition, some antibodies against CD3 partially inhibit CD3; clone SK7 is recommended for use in two-color experiments.
 

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