產(chǎn)品名稱：anti-mouse MD-1 PE MD113 100 ug 產(chǎn)品貨號：eBioscience 12-9931-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse MD-1 PE (To Be Discontinued) Also known as: MD1, Toll-like Receptor Clone: MD113 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-9931 Cat. No. Size 12-9931-81 50 ug 12-9931-82 100 ug Description: The MD113 monoclonal antibody reacts with mouse MD-1, a 28 kDa molecule, which physically associates with the extracellular portion of RP105 (CD180). MD-1 is expressed by mature B cells, monocytes/macrophages and dendritic cells. The coexpression of MD-1 is indispensable for cell surface expression of RP105 and LPS recognition and signaling. Several monoclonal antibodies to mouse MD-1, including MD14 and MD113, have been reported to be antagonistic for LPS-induced B cell proliferation and CD86 upregulation, while the anti-mouse CD180 (clone RP/14, Cat. No. 16-1801) is reported to exert potent mitogenic effect. MD113 has been reported to suppress LPS-induced B cell responses to a higher degree than MD14 (Cat. No. 14-9921).
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