eBioscience 12-9381-42 Phycoerythrin (PE) anti-human podoplanin 100 tests

產品名稱：Phycoerythrin (PE) anti-human podoplanin 100 tests
產品貨號：eBioscience 12-9381-42
產品規格：100 tests
Anti-Human Podoplanin PE
Also known as: PDPN
Clone: NZ-1.3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-9381
Cat. No. Size
12-9381-41  25 tests 
12-9381-42  100 tests 
Description: Podoplanin is a 40-kDa type I transmembrane sialomucin-like glycoprotein involved in platelet aggregation and cancer metastasis. This protein is expressed on lymphatic endothelial cells and follicular dendritic cells, as well as on many human cancers, including squamous cell carcinoma, glioblastoma, seminoma, and mesothelioma. Podoplanin expression has been demonstrated to be regulated by the Fos protein of the Activating Protein-1 (AP-1) transcription factor complex. Much of its functionality arises via interaction with its endogenous receptor, C-type lectin-like receptor-2 (CLEC-2).
This antibody has been reported to block the interaction between Podoplanin and CLEC-2.
 

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