eBioscience 12-8899-41 anti-human Granzyme B PE GB11 25 tests

產品名稱：anti-human Granzyme B PE GB11 25 tests
產品貨號：eBioscience 12-8899-41
產品規格：25 tests
Anti-Human Granzyme B PE
Clone: GB11
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-8899
Cat. No. Size
12-8899-41  25 tests 
Description: The GB11 antibody reacts with human Granzyme B (GrB). GrB is one of the family of serine proteases, known as granzymes, that is located in the granules of cytotoxic T cells and NK cells. Granzyme B has been described also as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation. GrB has been called CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. GrB is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved has been identified as mannose 6-phosphate receptor. This receptor functions as a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.
 

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!