eBioscience 12-8854-80 anti-mouse c-Met (HGFR) PE eBioclone 7 25 ug

產品名稱：anti-mouse c-Met (HGFR) PE eBioclone 7 25 ug
產品貨號：eBioscience 12-8854-80
產品規格：25 ug
Anti-Mouse c-Met (HGF Receptor) PE
Also known as: hepatocyte growth factor receptor
Clone: eBioclone 7
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-8854
Cat. No. Size
12-8854-80  25 ug 
12-8854-82  100 ug 
Description: The eBioclone 7 monoclonal antibody was generated against a mouse c-Met-Ig fusion protein, and reacts with mouse c-Met-transfected cells. Mouse c-Met (HGFR) is a 170 kDa receptor tyrosine kinase (RTK) expressed by epithelial cells of the brain, kidney, liver and other tissues. Binding of its ligand, Hepatocyte Growth Factor (HGF), triggers receptor autophosphorylation, and activation of several downstream effectors including the mitogen-activated protein kinases ERK-1 and ERK-2, and PLC gamma. Activation of the c-Met signal transduction pathway leads to mulitple cellular responses including cell motility, scattering, proliferation, survival and angiogenesis. Mutations in human c-Met have been implicated in the development of several malignancies.
 

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