eBioscience 12-7169-41 Phycoerythrin (PE) Human IL-17F 25 tests

產品名稱：Phycoerythrin (PE) Human IL-17F 25 tests
產品貨號：eBioscience 12-7169-41
產品規格：25 tests
Anti-Human IL-17F PE
Also known as: Interleukin-17F
Clone: SHLR17
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-7169
Cat. No. Size
12-7169-41  25 tests 
Description: The SHLR17 monoclonal antibody reacts with human interleukin (IL)-17F. IL-17F is a homodimeric, 34 kDa member of the IL-17 family, which includes IL-17(A), B, C, D, E (IL-25). Within this family, IL-17A and IL-17F are produced preferentially by T helper 17 (Th17) cells, with other members produced more widely. IL-17F and IL-17A have many overlapping functions, but knockout studies have shown each to have independent functions as well. In vitro cultured Th17 cells have been shown to express IL-17F and IL-17A homodimers and IL-17A/F heterodimers depending on the culture conditions and their differentiation state. A heterodimer of IL-17RA and IL-17RC has been shown to bind IL-17F, resulting in target cell-secretion of pro-inflammatory cytokines and chemokines, as well as neutrophil recruitment.
 

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