eBioscience 12-6981-80 Anti-Mouse ROR gamma (t) PE (B2D) 25 ug

產品名稱：Anti-Mouse ROR gamma (t) PE (B2D) 25 ug
產品貨號：eBioscience 12-6981-80
產品規格：25 ug
Anti-Mouse ROR gamma (t) PE
Also known as: Retinoid-Related Orphan Receptor gamma
Clone: B2D
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-6981
Cat. No. Size
12-6981-80  25 ug 
12-6981-82  100 ug 
Description: The B2D monoclonal antibody reacts with the mouse ROR gamma (t) protein. RORgamma is a member of the retinoic acid-related orphan receptor (ROR) family, which also includes ROR alpha and ROR beta. ROR family proteins are ligand-dependent transcription factors that play roles in multiple physiological processes. ROR gamma is expressed in several tissues including liver, lung, muscle, heart and kidney. Furthermore, it was discovered that alternative transcription results in the expression of an isoform, ROR gamma t, which is expressed exclusively in cells of the lymphoid compartment, namely CD4+CD8+ “double-positive” thymoyctes, Th17 cells of the periphery and lymphoid tissue inducer (Lti) cells of lymphoid organs.
The ROR gamma t isoform differs from RORγ by three unique amino acids at the amino terminus. Therefore, the B2D antibody will react with both the ROR gamma and ROR gamma t isoforms.
 

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