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eBioscience 12-6668-42 Anti-Human PARP1 (Cleaved) PE (HLNC4) 100 tests

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產品名稱: eBioscience 12-6668-42 Anti-Human PARP1 (Cleaved) PE (HLNC4) 100 tests
產品型號: 12-6668-42
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eBioscience 12-6668-42 Anti-Human PARP1 (Cleaved) PE (HLNC4) 100 tests


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eBioscience 12-6668-42 Anti-Human PARP1 (Cleaved) PE (HLNC4) 100 tests

產品名稱:Anti-Human PARP1  (Cleaved) PE (HLNC4) 100 tests
產品貨號:eBioscience 12-6668-42
產品規格:100 tests
Anti-Human PARP1 (Cleaved) PE
Also known as: poly ADP-ribose polymerase
Clone: HLNC4
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-6668
Cat. No. Size
12-6668-41  25 tests 
12-6668-42  100 tests 
Description: This HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116 kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85 kDa and 25 kDa.
The HLNC4 antibody specifically recognizes the 85 kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116 kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.
 

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