eBioscience 12-5986-82 anti-mouse B7-DC (CD273) PE TY25 100 ug

產品名稱：anti-mouse B7-DC (CD273) PE TY25 100 ug
產品貨號：eBioscience 12-5986-82
產品規格：100 ug
Anti-Mouse CD273 (B7-DC) PE
Also known as: B7DC, PD-L2, PDL-2, PDL2
Clone: TY25
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-5986
Cat. No. Size
12-5986-81  50 ug 
12-5986-82  100 ug 
12-5986-83  200 ug 
Description: The TY25 monoclonal antibody reacts with mouse B7-DC/PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of ~25 kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by sub-populations of dendritic cells, monocytes and macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, but binds PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. TY25 is a useful tool to study the exact function of B7-DC/PD-L2 in APC/T cell interaction and to characterize the expression pattern of this molecule in mouse.
 

產品留言

標題

聯系人

聯系電話

內容

驗證碼

點擊換一張

注：1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!