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eBioscience 12-5856-80 Phycoerythrin (PE) anti-mouse Ly-49A (Ly49A) 25 ug

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產品名稱: eBioscience 12-5856-80 Phycoerythrin (PE) anti-mouse Ly-49A (Ly49A) 25 ug
產品型號: 12-5856-80
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eBioscience 12-5856-80 Phycoerythrin (PE) anti-mouse Ly-49A (Ly49A) 25 ug


eBioscience 12-5856-80 Phycoerythrin (PE) anti-mouse Ly-49A (Ly49A) 25 ug  的詳細介紹
eBioscience 12-5856-80 Phycoerythrin (PE) anti-mouse Ly-49A (Ly49A) 25 ug

產品名稱:Phycoerythrin (PE) anti-mouse  Ly-49A (Ly49A) 25 ug
產品貨號:eBioscience 12-5856-80
產品規格:25 ug
Anti-Mouse Ly-49A PE
Also known as: Ly49A
Clone: A1 (Ly49A)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-5856
Cat. No. Size
12-5856-80  25 ug 
12-5856-82  100 ug 
Description: This A1 monoclonal antibody reacts with Ly49A, a 44-kDa member of the Ly49 family of type II transmembrane receptors expressed on natural killer (NK) cells. This receptor is present as a disulfide-linked homodimer with C-type lectin extracellular domains. An inhibitory receptor, Ly49A binds MHC class I molecules, such as H-2Dd, H-2Dk, and H-2DP, to inhibit NK-mediated cytotoxicity by triggering phosphorylation of its ITIM domain and recruitment of SHP-1 and SHP-2. Ly49A is expressed on DX5+CD3- NK cells and DX5+CD3+ NK T cells, as well as on a population of memory CD8+ T cells in C57BL/6, C57BL/10, and B10 congenic mice.
 

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