產(chǎn)品名稱：PE Mouse/human TdT (clone 19-3), 25 ug 產(chǎn)品貨號(hào)：eBioscience 12-5846-80 產(chǎn)品規(guī)格：25 ug Anti-Human/Mouse TdT PE Also known as: terminal deoxynucleotidyl transferase Clone: 19-3 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-5846 Cat. No. Size 12-5846-80 25 ug 12-5846-82 100 ug Description: This 19-3 monoclonal antibody recognizes human and mouse terminal-deoxynucleotidyl transferase (TdT), a 60 kDa polymerase responsible for the template-independent addition of N-nucleotides at gene segment junctions of developing lymphocytes. Expression is found in the nucleus of immature lymphocytes but not in mature lymphocytes or non-lymphoid cells. Tdt plays a critical role during TCR and Ig gene rearrangement. Regulation of expression in the mouse thymus correlates with T cell selection; decreased or absent after positive selection. Additionally Tdt has been shown to be present in lymphoma or lymphoblastic leukemia cells.
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