eBioscience 12-5783-81 anti-mouse Ly49A/D PE eBio12A8 (12A8) 50 ug

產品名稱：anti-mouse Ly49A/D PE eBio12A8 (12A8) 50 ug
產品貨號：eBioscience 12-5783-81
產品規格：50 ug
Anti-Mouse Ly-49A/D PE
Also known as: Ly49A, Ly49D
Clone: eBio12A8 (12A8)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-5783
Cat. No. Size
12-5783-81  50 ug 
Description: The eBio12A8 antibody reacts with Ly-49A and Ly-49D. The Ly-49 family of NK-cell receptors, members of the C-type lectin superfamily, are disulfide-linked type-II transmembrane protein homodimers with extracellular carbohydrate-recognition domains which bind to MHC class I alloantigens. The Ly-49 family members are expressed independently, such that an individual NK or T cell may display more than one class of Ly-49 receptor homodimers. Ly-49D is expressed on subsets of natural killer cells in C57BL/6, C3H/He, and SJL mice, but not DBA/2, AKR, CBA/J, or BALB/c mice. The Ly-49D antigen has not been detected on NK-1.1+ T cells. The Ly-49D receptor has been implicated in mediation of NK cell cytolysis. Ly-49D is an activating receptor while Ly-49A is a inhibitory receptor.
eBio12A8 does not react with BALB/c, DBA/2, AKR, or CBA/J Ly-D49D.
 

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