產(chǎn)品名稱:Canine CD45R PE (Clone: YKIX753.22) 100 tests 產(chǎn)品貨號(hào):eBioscience 12-5451-42 產(chǎn)品規(guī)格:100 tests Anti-Canine CD45R PE Clone: YKIX753.22 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-5451 Cat. No. Size 12-5451-41 25 tests 12-5451-42 100 tests Description: The YKIX753.22 monoclonal antibody reacts with canine CD45R. In dogs, CD45R is expressed on B cells and peripheral T cells. In addition, CD45 exists as multiple isoforms due to alternative splicing. Some isoforms of CD45 are CD45RA, CD45RB, or CD45RO depending on the exon used during transcription. The C-terminal domain of CD45 exhibits tyrosine phosphatase activity that enables signaling from by T cell and B cell receptors following activation. This antibody has been reported to promote cell depletion via antibody-dependent cell-mediated cytotoxicity when used in conjunction with YKIX716.13.
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