eBioscience 12-3172-81 anti-mouse PDCA-1 (pDC Ag-1, BST2, CD317) PE eBio927 50

產品名稱：anti-mouse PDCA-1 (pDC Ag-1, BST2, CD317) PE eBio927 50 ug
產品貨號：eBioscience 12-3172-81
產品規格：50 ug
Anti-Mouse CD317 (BST2, PDCA-1) PE
Also known as: plasmacytoid DC Ag-1, pDC Ag-1, BST 2, PDCA1
Clone: eBio927
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-3172
Cat. No. Size
12-3172-81  50 ug 
12-3172-82  100 ug 
Description: The eBio927 monoclonal antibody reacts with PDCA-1 (BST2, CD317), a specific marker of plasmacytoid dendritic cells (pDC), also known as type I IFN-producing cells (IPC) in the naïve mouse. Mouse IPCs are typically CD11c+, CD11b-, B220+, Ly-6C+, and CD62L+. PDCA-1 is predominantly expressed by IPCs in the naïve mouse which represents a very minor population (<0.5%) of splenocytes. It is upregulated on numerous cell types following stimulation which triggers an IFN response. PDCA-1 cycles between cell surface and intracellular compartments and may function to regulate trafficking of secreted cytokines. PDCA-1 (BST2) is the protein recognized by antibody 120G8.
The eBio927 monoclonal antibody has also been shown to have functional activity. The epitope recognized by eBio927 is distinct from eBio129c; thus, the antibodies can be used to costain, purify and identify pDCs.
 

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