產(chǎn)品名稱(chēng)：Anti-Rat CD314 (NKG2D) PE (11D5F4) 100 ug 產(chǎn)品貨號(hào)：eBioscience 12-3140-82 產(chǎn)品規(guī)格：100 ug Anti-Rat CD314 (NKG2D) PE Also known as: NKR-P2, KLRK1 Clone: 11D5F4 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-3140 Cat. No. Size 12-3140-80 25 ug 12-3140-82 100 ug Description: This 11D5F4 monoclonal antibody reacts with rat CD314, which is also known as NKG2D. This C-type lectin-like type II transmembrane protein is expressed on NK cells, subsets of T lymphocytes (e.g., CD8+ T cells and gammadelta T cells), NK T cells, and activated macrophages. The frequency of cells expressing NK2GD has been shown to vary among different rat strains. This receptor is involved in activating NK cell cytotoxicity, and has been reported to bind the MHC Class I-related ligands RAE-1L and RRLT to mediate allograft rejection in the rat. The 11D5F4 antibody has been reported to block killing and IFN gamma secretion by NK cells co-cultured with dendritic cells.
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