產(chǎn)品名稱：Anti-Human CD305 (LAIR-1) (clone NKTA255) PE, 100 tests 產(chǎn)品貨號：eBioscience 12-3059-42 產(chǎn)品規(guī)格：100 tests Anti-Human CD305 (LAIR1) PE Clone: NKTA255 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-3059 Cat. No. Size 12-3059-41 25 tests 12-3059-42 100 tests Description: This NKTA255 monoclonal antibody reacts with human CD305, which is also known as leukocyte-associated Ig-like receptor (LAIR) 1. CD305 is a type I transmembrane glycoprotein that possesses an extracellular Ig-like domain and two intracellular ITIMs. CD305 is expressed on nearly all immune cells, including T, NK, and B cells, as well as monocytes, dendritic cells, eosinophils, basophils, and mast cells. In humans, this molecule is also expressed on CD34+ hematopoietic progenitor cells and thymocytes. Several isoforms of CD305 exist due to alternative splicing, and their expression may differ between cell types. As an inhibitory receptor, CD305 blocks cytokine-mediated signaling, cell proliferation, and apoptosis. Studies have also identified collagens as the ligands for CD305. The NKTA255 antibody has been reported to inhibit NK cytolytic activity.
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