eBioscience 12-1588-41 Phycoerythrin (PE) anti-human CD158f (KIR2DL5) 25 tests

產品名稱：Phycoerythrin (PE) anti-human CD158f (KIR2DL5) 25 tests
產品貨號：eBioscience 12-1588-41
產品規格：25 tests
Anti-Human CD158f PE
Also known as: KIR2DL1/S1, KIR
Clone: UP-R1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-1588
Cat. No. Size
12-1588-41  25 tests 
12-1588-42  100 tests 
Description: This UP-R1 monoclonal antibody recognizes human CD158f, also known as KIR2DL5. CD158f is an inhibitory receptor and a member of the KIR (Killer cell Ig-like receptors) family of receptors, which recognizes subsets of HLA alleles. Expression is found mainly on a subset of NK cells with minimal expression also present on a minor subset of T lymphocytes in some individuals. This new member of the family is highly polymorphic and expression is not found on many human donors. Activation of the receptor and tyrosine phosphoryaltion recruits SHP-2 and SHP-1 to the ITIM cytoplasmic domain.
The UP-R1 antibody has been shown to inhibit NK cytotoxicity.
 

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