產(chǎn)品名稱：Anti-CD146 PE (P1H12) 100 tests 產(chǎn)品貨號(hào)：eBioscience 12-1469-42 產(chǎn)品規(guī)格：100 tests Anti-CD146 PE Also known as: Melanoma Cell Adhesion Molecule, MUC18, Mel-CAM, EndoCAM Clone: P1H12 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 12-1469 Cat. No. Size 12-1469-41 25 tests 12-1469-42 100 tests Description: The monoclonal antibody P1H12 recognizes CD146 also known as MUC18, s-endo, Endo-CAM and Mel-CAM, which is a member of the Ig superfamily of proteins. The expression of CD146 is found on endothelial cells, bone marrow fibroblasts and some tumors (especially melanoma). Recently mesenchymal stromal cells and endometrial stromal cells have also been shown to express CD146. The presence of CD146 on circulating blood cells have been confined to a subset of T cells rather than circulating endothelial cells, as expression of other endothelial markers (CD31 and CD51/61) is negative. Expression can be found on activated lymphocytes. The protein is heavily glycosylated with more than 50% of the mass from carbohydrates. The antibody P1H12 has been reported to crossreact to mouse, rabbit, canine, but not rat.
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