Phycoerythrin (PE) anti-human CD10 (CALLA) 25 tests **

產品名稱：Phycoerythrin (PE) anti-human CD10 (CALLA) 25 tests
產品貨號：eBioscience 12-0108-41
產品規格：25 tests
Anti-Human CD10 PE
Also known as: Common Acute Lymphocytic Leukemia antigen, Neprilysin, CALLA, NEP, Mme
Clone: SN5c
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 12-0108
12-0108-41  25 tests   
12-0108-42  100 tests 
Description: The eBioSN5c monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALLs). Subsequently, CD10 was shown to be the same molecule as neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallopeptidase acting on substrates such as endothelin, glucagon, gastrin, neurotensin and bradykinin. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and its expression has been reported on mature germinal center B cells. CD10 expression is also found on normal donor granulocytes and bone marrow stromal cells. Most likely, CB-CALLA and eBioSN5c see different epitopes due to their ability to co-stain.

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