Anti-Human c-Met (HGFR) FITC (97) **

產品名稱：Anti-Human c-Met (HGFR) FITC (97) 25 tests
產品貨號：eBioscience 11-8858-41
產品規格：25 tests
Anti-Human c-Met (HGF Receptor) FITC
Also known as: hepatocyte growth factor receptor
Clone: eBioclone 97
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 11-8858
11-8858-41  25 tests 
Description: The eBioclone 97 monoclonal antibody was generated against a human c-Met-Ig fusion protein, and reacts with human c-Met (HGFR)-transfected cells. Human c-Met is a 145 kDa receptor tyrosine kinase (RTK) expressed by epithelial cells of the brain, kidney, liver and other tissues. Binding of its ligand, Hepatocyte Growth Factor (HGF), triggers receptor autophosphorylation, and activation of several downstream effectors including the mitogen-activated protein kinases ERK-1 and ERK-2, and PLC gamma;. Activation of the c-Met signal transduction pathway leads to mulitple cellular responses including cell motility, scattering, proliferation, survival and angiogenesis. Mutations in human c-Met have been implicated in the development of several malignancies. 
 

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