anti-human CD146 (Muc 18, MCAM, Mel-CAM, EndoCAM) FITC P1H12 **
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產品名稱: anti-human CD146 (Muc 18, MCAM, Mel-CAM, EndoCAM) FITC P1H12 **
產品型號: 11-1469-41
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
anti-human CD146 (Muc 18, MCAM, Mel-CAM, EndoCAM) FITC P1H12 **
anti-human CD146 (Muc 18, MCAM, Mel-CAM, EndoCAM) FITC P1H12 **
的詳細介紹
anti-human CD146 (Muc 18, MCAM, Mel-CAM, EndoCAM) FITC P1H12 **
產品名稱：anti-human CD146 (Muc 18, MCAM, Mel-CAM, EndoCAM) FITC P1H12 25 tests
產品貨號：eBioscience 11-1469-41
產品規格：25 tests
Anti-CD146 FITC
Also known as: Melanoma Cell Adhesion Molecule, MUC18, Mel-CAM, EndoCAM
Clone: P1H12
RUO: For Research Use Only. Not for use in diagnostic
procedures.
SKU# 11-1469
Cat. No. Size
11-1469-41 25 tests
11-1469-42 100 tests
Description: The monoclonal antibody P1H12 recognizes CD146 also known as MUC18, s-endo, Endo-CAM and Mel-CAM, which is a member of the Ig superfamily of proteins. The expression of CD146 is found on endothelial cells, bone marrow fibroblasts and some tumors (especially melanoma). Recently mesenchymal stromal cells and endometrial stromal cells have also been shown to express CD146. The presence of CD146 on circulating blood cells have been confined to a subset of T cells rather than circulating endothelial cells, as expression of other endothelial markers (CD31 and CD51/61) is negative. Expression can be found on activated lymphocytes. The protein is heavily glycosylated with more than 50% of the mass from carbohydrates.
The antibody P1H12 has been reported to crossreact to mouse, rabbit, canine, but not rat.
