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Anti-Noxa Purified, **

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產品名稱: Anti-Noxa Purified, **
產品型號: 14-6046-82
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Anti-Noxa Purified, **


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Anti-Noxa Purified, **

產品名稱:Anti-Noxa Purified, 100 ug
產品貨號:eBioscience 14-6046-82
產品規格:100 ug
Anti-Noxa Purified Purified
Clone: Polyclonal
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-6046
Cat. No. Size
14-6046-82  100 ug 
Description: This polyclonal antibody recognizes human, mouse and rat Noxa , a 15 kDa protein involved in apoptosis. Noxa is a BH3-only member of the bcl2 pro-apoptotic family. Expression is dependent on p53 expression. Under hypoxic conditions the protein is induced via HIF1 alpha. Down-regulation or blocking expression leads to suppression of apoptosis; thereby suggesting a therapeutic use for reagents that reduce expression. Further supporting this is Noxa’s overexpression in mantle cell lymphoma. In immunoblots a higher molecular weight band (about 34 kDa) has also been observed.

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