LY 294002,LY294002,LY-294002
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產品名稱: LY 294002,LY294002,LY-294002
產品型號: Merck 440202-5MG
產品展商: 其他品牌
產品文檔: 無相關文檔
簡單介紹
LY 294002,LY294002,LY-294002
LY 294002,LY294002,LY-294002
的詳細介紹
LY 294002,LY294002,LY-294002
LY 294002
MERCK相關產品資料：
440202 LY 294002 ( LY 294002 )
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
A cell-permeable, potent, reversible and specific phosphatidylinositol 3-kinase inhibitor (IC50 = 1.4 µM) that acts on the ATP-binding site of the enzyme. Also inhibits nonhomologous DNA end-joining (NHEJ) activity of the 460 kDa phosphatidylinositol 3-like kinase DNA-PKcs, which is the catalytic subunit of DNA-activated protein kinase. Does not affect the activities of EGF receptor kinase, MAP kinase, PKC, Pl 4-kinase, S6 kinase, and c-Src even at 50 µM. Blocks the proliferation of cultured rabbit aortic smooth muscle cells without inducing apoptosis. A 10 mM (1 mg/325 µl) solution of LY 294002 (Cat. No. 440204) in DMSO is also available.
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Product number
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型號
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價格
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440202-5MG
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5 mg
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詢價
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產品信息
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Form
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Off-white solid
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Primary Target
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specific phosphatidylinositol 3-kinase inhibitor
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Primary Target IC50
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1.4 µM
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Molar mass
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307.4
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Protect from Light
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Yes
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Cell permeable
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Yes
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Purity
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≥98% by HPLC
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Solubility
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DMSO or EtOH
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Chemical formula
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C19H17NO3
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CAS number
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154447-36-6
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Store and ship information
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Storage
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-20°C
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Ship
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Ambient Temperature Only
Standard Handling
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